Knight-Wisdom's diving career began in 2004; he has said that he took up the sport after seeing it at the 2004 Summer Olympic Games. Knight-Wisdom has said of himself that "I am a 190 cm tall, 90 kg heavy, black diver... Watch a diving event and that is not something you will see very often." In 2012, Knight-Wisdom decided to represent Jamaica; he had been eligible to compete for Barbados or Great Britain, but had struggled to get in the British team. Knight-Wisdom competed at the 2014 Commonwealth Games, making him Jamaica's first-ever male Commonwealth diving competitor; Knight-Wisdom finished fifth in the 1 metre springboard event, and eleventh in the 3 metre springboard event. Knight-Wisdom competed in the 2016 FINA Diving World Cup; after qualifying for the semi-finals by finishing seventeenth, he qualified for the 2016 Summer Olympics, becoming the first male Jamaican diver at the Olympics, as well as the first male diver from any Caribbean nation. Knight-Wisdom finished second in the Diving World Cup final. After qualifying for Rio 2016, Knight-Wisdom was named Leeds Beckett University Sportsman of the Year for 2016.