According to O'Brien, in an effort to promote his company Scorpion Computer Services, Inc. and its service Concierge Up, he came up with the idea to create a television show. O'Brien contacted Scooter Braun who shopped the idea to CBS. In September 2014, CBS premiered the first season of the drama series, Scorpion, based on O'Brien's alleged life experiences. He serves as an executive producer for the series, and regularly contributes to story development. For his part in story development O'Brien consults with series writers on technical aspects of the plot, including how he would solve problems presented in the show's scripts. The technical aspects of the plot, however, were a reason for the National Science Teachers Association to advise teachers to use the show as an example of incorrect or exaggerated science in 2015. O'Brien also consults with Elyes Gabel, the actor who plays the fictional Walter O'Brien. In an interview with CBS News to promote the second season, Gabel said about O'Brien that "he's out saving the world or talking to, you know, princes of Liechtenstein. So every now and again, I get the chance to talk to him and he'll call me up. And sometimes we talk about the show. Sometimes we talk about characters."
The first season attracted more than 26 million viewers. CBS ordered a full season of Scorpion in October 2014 and renewed it for a second season in 2015. The show was renewed again for a third season in 2016, with a fourth seasoned confirmed for 2017. In March 2017, CBS renewed Scorpion for season 4. The show was cancelled after four seasons in May 2018.
In 2014, CNET, Techdirt, and Fast Company evaluated CBS' claims about O'Brien's accomplishments, widely reported in the media, following questions to Fast Company. The Irish Times said that "it is impossible to substantiate some claims." In a follow-up interview with Susan Karlin of Fast Company, O'Brien answered some of Karlin's questions but said that he was bound by non-disclosure agreements.
Karlin wrote that some community edited business directories showed O'Brien's company was much smaller than the 2,600 employees and $1.3 billion in revenues stated in Karlin's original article. For example, in 2014 an anonymous editor on Credibility.com recorded Scorpion Computer Services as having 1 employee with annual revenue of $66,000. Karlin points out that community edited business directories data may be unreliable, and O'Brien stated that most of the company consists of independent contractors who work remotely.