In 2010, Vekselberg was appointed President of the Skolkovo Foundation, a non-profit organization funded by a mix of private investors and the Russian government, with the goal of building a technology research hub in Russia. As its President, Vekselberg signed a deal for Cisco Systems to invest $1 billion over ten years into Skolkovo Foundation projects. The Federal Bureau of Investigations subsequently issued a statement claiming that the Skolkovo Foundation was being used by the Russian government to gain access to classified American technology. Through Vekselberg's close associate from 1999 to April 2018 Vladimir Kuznetsov who gained a director's seat and became a major shareholder in C5 Razor Bidco with an investment of £16.1 million in 2015, Vekselberg is closely linked to Andre Pienaar, who heads the cloud computing firm C5 Group's C5 Accelerate which provides a Cloud Accelerator Cluster to Europe, the United States, the Middle East, and Africa.
In May 2010 Vekselberg reported that he would be relocating from Zurich to the Zug canton, a region of Switzerland that still supports the lump sum tax policy which was abolished by Zurich.