The Carolina Panthers selected Boston in the fourth round (128th overall) in the 2014 NFL Draft. Boston was the tenth safety drafted in 2014.
On May 21, 2014, the Carolina Panthers signed Boston to a four-year, $2.62 million contract that includes a signing bonus of $101,367.
On June 4, 2014, it was reported that Boston underwent sports hernia surgery and would miss organized team activities after sustaining the injuring during rookie minicamp. On July 29, 2014, the Carolina Panthers activated Boston off of their physically unable to perform list. Boston suffered an injury during their first practice. Throughout training camp, Boston competed to be a backup safety against Robert Lester and Colin Jones. Head coach Ron Rivera named Boston the backup free safety, behind Thomas DeCoud, to begin the regular season.
Boston was inactive for the entire preseason and also missed the first five (Weeks 1–5) regular season games due to a groin injury. On October 12, 2014, Boston made his NFL debut during the Panthers' 37–37 tie at the Cincinnati Bengals in Week 6. On October 30, 2014, Boston earned his first career start after Thomas DeCoud was ruled inactive due to a hamstring injury. He finished the Panthers' 28–10 loss to the New Orleans Saints with a season-high seven combined tackles in Week 9. Boston and cornerback Bene Benwikere became starters in Week 14 after defensive coordinator Sean McDermott opted to bench free safety Thomas DeCoud and cornerback Antoine Cason. On December 28, 2014, Boston recorded two solo tackles, broke up a pass, and returned his first career interception for the first touchdown of his career during a 34–3 win at the Atlanta Falcons. Boston made his first career interception off a pass attempt by Matt Ryan and returned it for an 84-yard touchdown in the third quarter. He finished his rookie season in 2014 with 26 combined tackles (18 solo), three pass deflections, one interception, and one touchdown in 11 games and five starts. Boston missed just one tackle and allowed just five receptions on 222 coverage snaps as a rookie, which ranked fourth-best among all safeties in 2014.