Bø became a regular fixture in the Norwegian team in the 2010–11 season. He started the season with a fourth place in the individual discipline in Östersund, Sweden, followed by a fifth and fourth place in the sprint and pursuit disciplines, respectively. On 5 January 2007, Bø won his first World Cup event, the sprint race in Hochfilzen, Austria, beating runner-up Serguei Sednev by 27.5 seconds. One day later, he won his second World Cup victory in the pursuit discipline. On 12 December, he was part of the winning Norwegian relay team. After his highly successful races in Hochfilzen, Bø took the yellow bib of the Overall World Cup leader. In the races in Pokljuka, Bø finished 12th in the individual discipline and second in the sprint. In Oberhof, Bø claimed his third and fourth World Cup victories (mass start and sprint). At the World Cup stops in February in the United States, Bø continued his good form; his worst result was a sixth place. In Presque Isle, Maine, he came in fourth in the sprint discipline. One week later in Fort Kent, Maine, Bø finished all three races in third place (sprint, pursuit and mass start).