Sulakshana had a singing career alongside her acting one. She began her singing career as a child singer singing the popular song "Saat Samundar Paar se" with Lata Mangeshkar in the 1967 film Taqdeer. Thereafter, she recorded with famed musicians such as Hemant Kumar and Kishore Kumar. She sang in Hindi, Bengali, Marathi, Oriya and Gujarati. In 1980, she released an album titled Jazbaat (HMV), wherein she rendered ghazals. She sang duets with accomplished singers such as Lata Mangeshkar, Mohammed Rafi, Kishore Kumar, Shailender Singh, Yesudas, Mahendra Kapoor and Udit Narayan. She sang under music directors such as Shankar Jaikishan, Laxmikant Pyarelal, Kalyanji Anandji, Kanu Roy, Bappi Lahiri, Usha Khanna, Rajesh Roshan, Khayyam, Rajkamal and several others. In 1986, Sulakshana was one of the singers to perform at the Royal Albert Hall in London to celebrate the "Festival of Indian Music" Concert along with acclaimed Music Directors Laxmikant Pyarelal and singers Manhar, Shabbir Kumar, Nitin Mukesh and Anuradha Paudwal.