In August 2009, Moyer became engaged to actress Anna Paquin, who played his character's love interest, Sookie Stackhouse, in the HBO series True Blood. They had been dating since filming the series pilot in 2007. The couple married on 21 August 2010 at a private residence in Malibu, California. Moyer and Paquin have a son and a daughter who are fraternal twins. The family resides in Venice, Los Angeles.