Sendhil Ramamurthy

Ramamurthy was born in Chicago to a Hindu family who had emigrated from India; his father was a Kannadiga and mother a Tamil. He grew up speaking English and a little Kannada. His parents are physicians. He has one sister who is also a physician. He and his sister were raised in San Antonio. There, he went to Keystone School and graduated in 1991.

Ramamurthy attended Tufts University initially as a pre-med major to follow in his parents' footsteps. He was also a member of the Kappa Charge of Theta Delta Chi. He became interested in acting when he took an "Intro to Acting" class during his junior year as part of his graduation requirement. After participating in several plays—including Our Country's Good, he chose to change career goals. He graduated with a bachelor's degree in history and then attended the Webber Douglas Academy of Dramatic Art in London in 1996, graduating in 1998.

In 2000, he appeared in NBC's television biblical miniseries In the Beginning in the role of Adam.

Ramamurthy joined the cast of the USA Network show Covert Affairs as Jai Wilcox from the second episode onward, replacing character Conrad Sheehan III, played by Eric Lively in the pilot. The show premiered in July 2010. In the season 3 premiere, his character was killed off.

On December 19, 2012, it was announced that he would appear in the CW show Beauty & the Beast as Gabriel Lowen, an assistant district attorney.

He appeared in his Heroes role in that series's continuation entitled Heroes Reborn, in 2015 and 2016.

As of 2020, he is part of the cast of the new Netflix series Never Have I Ever, playing Mohan Vishwakumar, the main character's father. The series is produced by Mindy Kaling, who had first worked with Ramamurthy when she was a writer-performer on The Office.