Rodolfo Pizarro

Pizarro started his youth career with Orinegros Ciudad Madero, and joined the Pachuca Youth System in 2011. Pizarro made his debut with the senior team on 14 September 2012 coming in on as a substitute in the 71st minute in a 3–2 win over Morelia. At the time of his debut, he played as a right-back.

On 19 February 2013, during a Copa MX group stage match against Dorados de Sinaloa, he would score his first goal in a 5–2 loss.

Pizarro was included by Raúl Gutiérrez to participate in the 2014 Toulon Tournament. Mexico would fail to qualify to the next round after placing third in the group stage.

On 29 January 2014, Pizarro made his debut for the senior squad in a friendly game against South Korea, playing all 90 minutes. On 10 February 2016, Pizarro scored his first goal for Mexico in the 87th minute of the friendly match against Senegal, with the match finishing 2–0.

On 18 September 2015, Rodolfo Pizarro was selected by coach Raúl Gutiérrez to play in the CONCACAF Men's Olympic Qualifying Championship. Mexico went on to win the tournament and qualified for the 2016 Summer Olympics as Pizarro was named to the tournament's Best XI.

In December 2016, Pachuca announced Pizarro was transferred to Guadalajara for a reported $15 million, in a deal that saw Víctor Guzmán go the other way, permanently joining Pachuca. On 7 January 2017, Pizarro made his debut against Club Universidad Nacional, playing the whole match in which Guadalajara won 2–1. A week later, Pizarro scored his first goal for Guadalajara against Monterrey from a long range shot, the game ended 2–2.

On 7 July 2016, Pizarro was named in Mexico's 18-man squad that would participate in the 2016 Summer Olympics in Rio de Janeiro, Brazil. In Mexico's first group stage match against Germany, he scored Mexico's second goal to make the game 2–1 but was eventually tied 2–2. In Mexico's second group stage match against Fiji, Pizarro along with teammate Oribe Peralta, would pick up injuries. They were subsequently replaced by Carlos Fierro and Raúl López Gómez.

On 28 June 2017, Pizarro was called up to participate in the 2017 CONCACAF Gold Cup. In the quarter-final match against Honduras, he scored the only goal of the match at the 4th minute, winning 1–0.

On 4 June 2018, after much media speculation, Guadalajara sporting director Francisco Gabriel de Anda officially announced that Pizarro was being transferred to fellow league club Monterrey, for a reported $16 million, making him the costliest interleague transfer in Liga MX history. Rejoining former Pachuca manager Diego Alonso, Pizarro would make his debut with Monterrey on 21 July 2018 in a 1–0 victory against his youth club, Pachuca. On November 5, he would score his first goal with the team in a 2–0 win over Veracruz.

With the arrival of Gerardo Martino as Mexico's new coach, Pizarro has been given precedence. In March 2019, Pizarro declared that it was a motivating gesture that Martino treated the domestic league players with the same importance and opportunity as those based in Europe. He was included in Mexico's preliminary list for the 2019 CONCACAF Gold Cup and was eventually in the final list. Prior to the start of the Gold Cup, he picked up a minor injury and did not appear in the tournament until the final group stage match against Martinique, coming on as a half-time substitute and contributing an assist to Raúl Jiménez for Mexico's second goal in a 3–2 victory. In the final against the United States, during the first half he would bend his left elbow in an apparent injury but managed to play in the second half as well, managing to contribute in Mexico's build up play for the winning goal as they won the tournament.

On 14 February 2020, Pizarro left Monterrey for Major League Soccer expansion side Inter Miami, following a protracted dispute between the clubs about the activation of his release clause, rejoining head coach Diego Alonso for a third time, his coach at both Pachuca and Monterrey. The following day, despite not officially being announced as a signing for the club, Pizarro scored the first goal for Miami in a 2–1 preseason friendly loss to Philadelphia Union. That same day, Monterrey filed a complaint with FIFA against Pizarro and Inter Miami for improper contact between the player and Inter Miami co-owner David Beckham while Pizarro was still under contract with Monterrey. FIFA's investigation was still on-going when news of the complaint broke on 4 March.

Inter Miami CF officially signs Rodolfo Pizarro, fills second designated player slot

It took them a little longer than they originally wanted, but Inter Miami CF has signed their second designated player. The club announced on Monday that it signed Mexican national team midfielder Rodolfo Pizarro. The transaction comes after Mexican club Monterrey said on Wednesday that Pizarro "unilaterally rescinds his contract with [the club] due to his desire to continue his sports career ...