In August 2011, Zuckerberg resigned from Facebook and announced her new social media firm, named "Zuckerberg Media". Since starting Zuckerberg Media, Randi has produced shows and digital content for BeachMint, the Clinton Global Initiative, Cirque du Soleil, the United Nations, Condé Nast and Bravo.
In 2011 Zuckerberg advocated for the abolition of anonymity on the Internet to protect children and young adults from cyber-bullying. Zuckerberg explained how anonymity is protective for perpetrators.