On March 21, 2011, Pusha T released his solo debut, a mixtape titled Fear of God, which included "My God" and featured both freestyles and original songs, and included features from Kanye West, 50 Cent, Rick Ross, Pharrell Williams and Kevin Cossom. The mixtape was well received, and soon after he began working on his debut extended play (EP) Fear of God II: Let Us Pray, which initially included four songs from the mixtape and five new songs. The EP was originally set to be released on June 21, 2011; however, it was pushed back to August 23, and for a while September 27 was believed to be the date, but after it came and went, on October 6, 2011, Pusha T announced the EP was set to be released on November 8, 2011. In addition, it was revealed he had added four more songs to the EP, bringing it to 12 tracks in total. Considered a re-release of the initial Fear of God, it was released on November 8, 2011 and was well received by critics.
The first single from Fear of God II: Let Us Pray was leaked onto the Internet on July 8, 2011. The song, titled "Trouble on My Mind", features Odd Future frontman Tyler, The Creator. The EP's second single, "Amen", was released September 13, 2011. The song, originally meant for Young Jeezy, was produced by Shawty Redd and features verses from Kanye West and Young Jeezy, respectively. After the EP's release on November 8, the project debuted at number 66 on the Billboard 200 with 8,900 copies sold in its first week released. It also entered at number ten on Billboard's R&B/Hip-Hop Albums, at number eight on Billboard's Top Rap Albums, and at number 25 on its Digital Albums chart.
In 2011, Pusha T appeared on the second season of the HBO series How to Make It in America. He played the role of a henchman for Urban Caribbean League. After the release of his EP, Pusha T started working on his solo debut studio album, which would be executively produced by Kanye West. Pusha also said that after the release of his solo debut album and the Re-Up Gang mixtape, Long Live the Cane, Clipse would also reunite and release another album. In late 2011, Pusha made a guest apparance on English pop singer Pixie Lott's "What Do You Take Me For?", the second single from her second studio album Young Foolish Happy. The song was a hit single in the UK, peaking at number ten on the UK Top 40.
On October 19, 2011 via Twitter, Kanye West announced plans for a Spring 2012 GOOD Music album, featuring all artists from the label as well as numerous guest appearances. On April 6, 2012, "Mercy", the lead single from the GOOD Music compilation album Cruel Summer was released. The song, produced by newly signed in-house producer Lifted, features Pusha T along with Kanye West, Big Sean and southern rapper 2 Chainz. On May 24, 2012, Pusha T released a song titled "Exodus 23:1" featuring The-Dream. It is speculated that the song is a diss track aimed at Young Money rappers Drake and Lil Wayne. This resulted in a diss-song by Lil Wayne, which Pusha T did not directly respond to, but branded it as "horrible" in an interview. He was featured alongside West on the third single for Cruel Summer - "New God Flow". In October 2012, Pusha T made an appearance on the soundtrack to the film The Man with the Iron Fists on a track titled "Tick Tock" alongside fellow American rappers Raekwon, Joell Ortiz and Danny Brown.
After Pusha T released "My God", the first single from his solo mixtape, his former GOOD Music label-mate Consequence took to Twitter and claimed Pusha T stole his flow and lyrics from a song of his that Pusha T was supposed to appear on, titled "The Last Supper". On July 22, 2011, Consequence released a song titled "The Plagiarist Society" where he takes shots and questions Pusha T's coke-dealing raps. Towards the end of the record, the Queens native promises to take aim at Kanye West next saying "You're nothing but a body shield, for that coward from the mid-west/ so yes you can bet, that your boss is next". Pusha T responded to the diss track when he appeared on Chicago's 107.5 WGCI's The Morning Riot and said nobody is looking for Consequence, as for if he would respond on a record, Pusha T went on to say "At the end of the day I am an artist and this whole rap thing is fun to me, so I can't say you won't hear nothing, but to go back and forth with him, it's not right, I won't get anything out of it." Later that day, Consequence called into Chicago's WGCI's The Morning Riot in retaliation to the remarks Pusha T made about him. He also premiered a song titled "Everybody Told Me 2 (Straighten It Out)" where he disses West, Pusha T and GOOD Music in general. Since then Pusha T has responded to Consequence on a record. The song was the remix to Ace Hood's "Go 'N' Get It" which also featured Beanie Sigel, Busta Rhymes and Styles P. In the song Pusha raps "Consequence, nigga, talk is cheap You don't want a problem? Off the beef Before I off his ass with his awful teeth". On August 19, Consequence released Movies on Demand 3 and continued to diss his former label and Pusha T on songs such as "Career Killer" and "Mr.RapFix (Hot Water)". On September 15, 2011 Consequence appeared on MTV's Rap Fix and announced his feud with Kanye West and GOOD Music was over. While out in Chicago in October 2011, Pusha T appeared on WGCI radio for a second time, and confirmed that the "beef" was indeed over, that it had died out and they have moved on. In January 2015, the two officially ended the feud when Consequence took to his Instagram page to let the people know: "All G.O.O.D. in 2015, Pusha [T] and I deaded everything and we creatively vibed with Kanye for this new LP."