In her 2010 autobiography, May-Treanor stated both of her parents were alcoholics. She also asserted her mother would at times become violent when drinking. From the age of 4 to 15, she lived with her grandparents. In 1988, her father committed to living his life sober after an automobile accident in which he struck and nearly killed a motorcyclist.
For the 2010 season, with Walsh Jennings taking a break from competition for the birth of her second son, May-Treanor teamed up with Branagh. The two won several tournaments together, but struggled for much of the year.
In her 2010 memoir, May-Treanor revealed she had been sexually assaulted while in college, pressed charges against her assailant, and testified at the trial.