She later appeared there as Adina in Donizetti's L'elisir d'amore, Liù in Puccini's Turandot, Marguerite in Gounod's Faust, Juliette in Roméo et Juliette, as Susanna, Micaela and Manon Lescaut. The following year she sang Mimì again for her Philadelphia Lyric Opera Company debut, with Flaviano Labò as Rodolfo. From the early 1970s into the 1980s, Freni sang heavier Verdi roles, including Elisabetta in John Dexter's production of Don Carlos, Desdemona in Otello (alongside Jon Vickers), Amelia in Simon Boccanegra, Elvira in the Luca Ronconi staging of Ernani, Leonora in La forza del destino, and the title role of Aida performed in the Houston Grand Opera in 1987. She appeared as Puccini's Tosca only on a recording. She performed as Manon Lescaut in the Metropolitan Opera's 1990 season, and recorded Madama Butterfly and the three roles of Il trittico.