On 25 May 1968, the day before her 11th birthday, Mary Bell strangled 4-year-old Martin Brown in a derelict house. She was believed to have committed this crime alone. Between then and a second killing, she and a friend, Norma Joyce Bell (1955–1989; no relation), aged 13, broke into and vandalised a nursery in Scotswood, leaving notes that claimed responsibility for the killing. The police dismissed this incident as a prank.
On 31 July 1968, the two girls took part in the strangulation death of 3-year-old Brian Howe on wasteland in the same Scotswood area. Police reports concluded that Mary Bell later returned to his body to carve an "M" into the boy's abdomen and used scissors to cut off some of his hair, scratch his legs, and mutilate his genitals.
On 17 December 1968, at Newcastle Assizes, Norma Bell was acquitted but Mary Bell was convicted of manslaughter on the grounds of diminished responsibility. The jury took their lead from her diagnosis by court-appointed psychiatrists who described her as displaying "classic symptoms of psychopathy". The judge, Justice Cusack, described her as dangerous and said she posed a "very grave risk to other children". She was sentenced to be detained at Her Majesty's pleasure, effectively an indefinite sentence of imprisonment. She was initially sent to Red Bank secure unit in Newton-le-Willows, Lancashire – the same facility that would house Jon Venables, one of James Bulger's killers, 25 years later.