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Glasberg graduated from Hewlett High School in 1974, and interned at the nearby radio station WLIR. She graduated from Hofstra University. She co-hosted a radio show from 1990 to 1999 on Hot 97 FM with Ed Lover and Doctor Dré. In 2002, they helped launch Power 105.1. For three years, she worked on WOR.
In 2006, Glasberg joined Howard 100 News, Howard Stern's news team at Sirius XM Satellite Radio. Stern stated in March 2015 that she was no longer with the show. She has been a correspondent for E!'s "Gossip Show", Real TV, WCBS-TV New York and ESPN2's coverage of the New York City Marathon, and is also the voice of 'Running' on the YES Network. On June 18, 2013, she released her first book titled Sex, Lies, and Cookies: An Unrated Memoir.
Glasberg was featured on the May/June 2011 cover of Making Music magazine to discuss her life with music.