The Case for Christ book summarizes Lee's interviews with thirteen evangelical Christian scholars—Craig Blomberg, Bruce Metzger, Edwin Yamauchi, John McRay, Gregory Boyd, Ben Witherington III, Gary Collins, D. A. Carson, Louis Lapides, Alexander Metherell, William Lane Craig, Gary Habermas, and J. P. Moreland—in which they defend their views regarding the historical reliability of the New Testament. Strobel's personal experience while encountering these scholars and their beliefs was portrayed in the 2017 drama film of the same name.
A film entitled The Case for Christ, based on Strobel's book, had its theatrical release in April 2017. The film was directed by Jonathan M. Gunn and is about an atheist reporter who tries to prove Christianity to be a cult. The film was produced by Triple Horse Studios and distributed by Pure Flix Entertainment.