Jenner met with Ryan Seacrest in 2007 to pursue a reality television show based on her family. Seacrest, who had his own production company, decided to develop the idea, having the popular family-based show The Osbournes in his mind. Jenner further commented on the possible series:
The show eventually was picked up to air on the E! cable network with Jenner acting as the executive producer. The series focuses on the personal and professional lives of the Kardashian–Jenner blended families. The series debuted on October 14, 2007, and has become one of the longest-running reality television shows in the country. The 18th season of Keeping Up with the Kardashians started airing on March 26, 2020. The show has resulted in the development of several spin-offs, such as Kourtney and Khloé Take Miami (2009), Kourtney and Kim Take New York (2011), Khloé & Lamar (2011), Rob & Chyna (2016) and Life of Kylie (2017)