Some Several women, that have worked close with the actor, have publicly accused Juan Darthés of sexual misconduct. The first one of them was Calu Rivero, who accused him of sexual harassment during the filming of Dulce amor. Darthés in turn filed a suit against Rivero, accusing her of defamation, although Darthés then failed show up to the first court hearing in December 2018. Rivero's accusations were followed by the actresses Natalia Juncos and Ana Coacci, who denounced similar actions during the filming of Gasoleros back in 1999. Darthés also accused them of defamation.
In December 2018, the actress Thelma Fardin, who was also part of the cast of Patito Feo, accused that Darthés raped her when he was 45 and she was 16. The event would have taken place in a hotel in Nicaragua, when the cast was making an international tour for the Patito Feo CD. She announced it during a press conference, joined by a statement signed by several Argentine actresses. Darthés denies all of these sexual misconduct accusations.