On May 7, 2011, Meals worked behind the plate for Justin Verlander's second career no-hitter. The umpire's ball four call on J. P. Arencibia in the eighth inning prevented Verlander from achieving a perfect game. However, Verlander later said that he agreed with the call.
Meals and Major League Baseball both acknowledged that he missed a call in the 19th inning of a game between the Pittsburgh Pirates and the Atlanta Braves on July 26, 2011. With respect to length of time, the game was the longest in Pirates history. During the play in question, a ground ball, Pirates catcher Michael McKenry received a throw and appeared to tag Braves runner Julio Lugo three feet in front of home plate but Meals called him safe and the Braves won the game. Meals received criticism for the call and the Pirates issued a public complaint. MLB executive vice president for baseball operations Joe Torre responded to the complaint and officially acknowledged that Meals' call was an error. However, other commentators have stated that the call was not obviously incorrect and that it may not have been overturned under MLB's current instant replay rules.