In Lovelock's 2006 book, The Revenge of Gaia, he argues that the lack of respect humans have had for Gaia, through the damage done to rainforests and the reduction in planetary biodiversity, is testing Gaia's capacity to minimize the effects of the addition of greenhouse gases in the atmosphere. This eliminates the planet's negative feedbacks and increases the likelihood of homeostatic positive feedback potential associated with runaway global warming. Similarly the warming of the oceans is extending the oceanic thermocline layer of tropical oceans into the Arctic and Antarctic waters, preventing the rise of oceanic nutrients into the surface waters and eliminating the algal blooms of phytoplankton on which oceanic food chains depend. As phytoplankton and forests are the main ways in which Gaia draws down greenhouse gases, particularly carbon dioxide, taking it out of the atmosphere, the elimination of this environmental buffering will see, according to Lovelock, most of the earth becoming uninhabitable for humans and other life-forms by the middle of this century, with a massive extension of tropical deserts. (In 2012, Lovelock distanced himself from these conclusions, saying he had "gone too far" in describing the consequences of climate change over the next century in this book.)
Writing in the British newspaper The Independent in January 2006, Lovelock argued that, as a result of global warming, "billions of us will die and the few breeding pairs of people that survive will be in the Arctic where the climate remains tolerable" by the end of the 21st century. He has been quoted in The Guardian that 80% of humans will perish by 2100 AD, and this climate change will last 100,000 years. He further predicted, the average temperature in temperate regions would increase by as much as 8 °C and by up to 5 °C in the tropics, leaving much of the world's land uninhabitable and unsuitable for farming, with northerly migrations and new cities created in the Arctic. He predicted much of Europe will have become uninhabitable having turned to desert and Britain will have become Europe's "life-raft" due to its stable temperature caused by being surrounded by the ocean. He suggested that "we have to keep in mind the awesome pace of change and realise how little time is left to act, and then each community and nation must find the best use of the resources they have to sustain civilisation for as long as they can."
Lovelock has been awarded a number of prestigious prizes including the Tswett Medal (1975), the American Chemical Society Award in Chromatography (1980), the World Meteorological Organization Norbert Gerbier–MUMM Award (1988), the Dr A.H. Heineken Prize for Environmental Sciences (1990) and the Royal Geographical Society Discovery Lifetime award (2001). In 2006 he received the Wollaston Medal, the Geological Society of London's highest award, whose previous recipients include Charles Darwin. Lovelock was appointed a Commander of the Order of the British Empire (CBE) for services to the study of the Science and Atmosphere in the 1990 New Year Honours and a Member of the Order of the Companions of Honour (CH) for services to Global Environment Science in the 2003 New Year Honours.