In 2013, D'Acampo launched a chain of restaurants with his name followed by My Pasta Bar or My Restaurant, with five restaurants. His first Pasta Bar opened on Fleet Street in July 2013. There are also restaurants in Leadenhall Market, Bishopsgate, Euston railway station, The Manchester Corn Exchange, and Camden Town (Gino D'Acampo My Restaurant).
Since 2013, D'Acampo has presented seven series of Gino's Italian Escape on ITV. A cookery book is released to accompany each series.