Elizabeth's response to the lack of marriage prospects was to take Alexis Shubin, a handsome sergeant in the Semyonovsky Guards regiment, as her lover. When Empress Anna found out about this, she had Shubin's tongue cut off and banished him to Siberia. After consoling herself, Elizabeth turned to handsome coachmen and footmen for her sexual pleasure. She eventually found a long-term companion in Alexis Razumovsky, a kind-hearted and handsome Ukrainian peasant serf with a good bass voice. Razumovsky had been brought from his village to St. Petersburg by a nobleman to sing for a church choir until the Grand Duchess purchased the talented serf from the nobleman for her own choir. A simple-minded man, Razumovsky never showed interest in affairs of state during all the years of his relationship with Elizabeth, which spanned from the days of her obscurity to the height of her power. As the couple was devoted to each other, there is reason to believe that they might even have married in a secret ceremony. In 1742, the Holy Roman Emperor made Razumovsky a Count of the Holy Roman Empire. In 1756, Elizabeth made him a Prince and Field Marshal.
Elizabeth crowned herself Empress in the Dormition Cathedral on 25 April 1742 (O.S.), which would become standard for all emperors of Russia until 1896. At the age of thirty-three, with relatively little political experience, she found herself at the head of a great empire at one of the most critical periods of its existence. Her proclamation explained that the preceding reigns had led Russia to ruin: "The Russian people have been groaning under the enemies of the Christian faith, but she has delivered them from the degrading foreign oppression." Russia had been under the domination of German advisers, so its Empress exiled the most unpopular of them, including Heinrich Ostermann, Burkhard von Munnich and Carl Gustav Lowenwolde. She passed down several pieces of legislation that undid much of the work her father had done to limit the power of the church., while still limiting its influence.
In 1742, the imperial government at Saint Petersburg ordered a Russian military expedition to conquer the Chukchis and Koryaks, but the expedition failed and its commander, Major Dmitry Pavlutsky, was killed in 1747. On 12 March 1747, a party of 500 Chukchi warriors raided the Russian stockade of Anadyrsk. By 1750, it had become clear the Chukchi would be difficult to conquer. The Empress then changed her tactical approach and established a formal peace with them.
As an unmarried and childless empress, it was imperative for Elizabeth to find a legitimate heir to secure the Romanov dynasty. She chose her nephew, Peter of Holstein-Gottorp. The young Peter had lost his mother at three months old and his father at the age of eleven. Elizabeth invited her young nephew to Saint Petersburg, where he was received into the Orthodox Church and proclaimed the heir to the throne on 7 November 1742. Keen to see the dynasty secured, Elizabeth immediately gave Peter the best Russian tutors and settled on Princess Sophie of Anhalt-Zerbst as a bride for her heir. Incidentally, Sophie's mother, Joanna Elisabeth of Holstein-Gottorp, was a sister of Elizabeth's own fiancé, who had died before the wedding. On her conversion to the Russian Orthodox Church, Sophie was given the name Catherine in memory of Elizabeth's mother. The marriage took place on 21 August 1745. Nine years later a son, the future Paul I, was born on 20 September 1754.