Sednaoui has also appeared in Love Lasts Three Years, released by Europa in January 2012, and The Legend of Kaspar Hauser, a surrealistic adaptation of the 19th century Teutonic foundling story transposed to Sardinia.
In addition to film, Sednaoui has appeared in campaigns for Chanel Eyewear, Giorgio Armani and a Roberto Cavalli fragrance campaign in February 2012, shot by Steven Klein for print and Johan Renck for television. In December 2015 she collaborated with Oscar-winning director Paolo Sorrentino on his campaign for Missoni Fragrance. Before his death during February 2019, Sednaoui served as a muse to Karl Lagerfeld.