From September 2015 until June 2016, she was a food stylist and panelist on Tyra Banks's syndicated daytime talk show, FABLife. In February 2016, Teigen published a book titled Cravings: Recipes for All of the Food You Want to Eat, which went on to become a New York Times bestseller and the second-best selling cookbook of the year. The following year, she released a clothing line in collaboration with the fashion company Revolve. In September 2018, Teigen released her second book, titled Cravings: Hungry For More. Simultaneously, she released a line of cookware through Target.
Teigen made donations to nonprofit organization Planned Parenthood in 2015 following the Colorado Springs Planned Parenthood shooting and again in 2017. She and her husband donated $25,000 to March for Our Lives, a rally against gun violence, in 2018. A supporter of immigrants' rights, she delivered a speech at a Families Belong Together event in Los Angeles that same year. In May 2020, Teigen donated $200,000 to bail and legal defense funds to aid activists arrested during protests in response the killing of George Floyd.