In 2015, Chi Pu marked a milestone in her acting career with her leading role in Yêu (Love). The LGBT movie won big in the box office and grossed more than half million USD within three days of its release. It also won the Golden Apricot Blossom Awards for Best Movie in 2015. Yêu won Chi Pu nominations for Best Actress at the 2015 Golden Apricot Blossom Awards and Green Star Awards. In 2015, Chi Pu was the backstage host for Dancing with the Stars Kids Vietnam - Season 2. In 2016, Chi Pu was one of the two hosts for The Voice Kids Vietnam - Season 4. Chi Pu was the judge for several beauty and style competitions, such as Miss Panasonic Beauty 2015 and Shine Your Style Contest with L'Officiel Vietnam's editorial secretary Angie Nguyễn and Lý Quí Khánh.
In 2015, Chi Pu was honored as Upcoming Female Actress at ELLE Style Awards by ELLE Vietnam. Chi Pu was the first Vietnamese actress who partnered with a fashion brand to launch her own collection. Chi Pu partnered with TheBlueTshirt and PUSW to launch two fashion collections. She used to work for Innisfree, Pepsi, Heineken, Panasonic Beauty, Nestea, and Cornetto. She is currently brand ambassador for Yamaha Janus, Dove Vietnam, OPPO Cameraphone. In April 2016, Chi Pu was the first Vietnamese artist to cooperate with Google in their Google App advertising campaign in Vietnam.
In 2015, Chi Pu was one of the ambassadors for “Về đi Vàng ơi” (Come home Golden), a campaign launched by Asia Canine Protection Alliance (ACPA). The campaign called for an end to the theft, trade, and cruel actions of dogs. Along with other artists, Chi Pu encouraged people to stop hunting and consuming rhino horns in Vietnam.