In the 2019 Indian general election, Supriyo again won from the Asansol Lok Sabha constituency as a Bharatiya Janata Party candidate defeating Moon Moon Sen by 1.97 lakh votes, and securing a total of 6.32 lakh votes. In May 2019, he became Minister of State for Environment, Forest and Climate Change.
On 19 September 2019, Supriyo was attacked by students after he was invited to attend an event at Calcutta's Jadavpur University.
On 13 August 2019, Supriyo Babul, accused the state government of not giving food for the cyclone affected people in Fazarganj for 5 days.