Ann Druyan

Druyan's first novel, A Famous Broken Heart, was published in 1977.

Druyan has for many years been a vocal advocate for nuclear disarmament. She was arrested three times at the Mercury, Nevada nuclear test site during Mikhail Gorbachev's unilateral moratorium on underground nuclear testing, with which President Ronald Reagan did not cooperate. This included an arrest in June 1986, when Druyan crossed a white painted line indicating the test site's boundary; Sagan, who attended the same protest with Druyan, was not arrested.

An asteroid discovered in 1998 was named in Druyan's honor by its discoverer Eleanor F. Helin. In a 2020 interview with Skeptical Inquirer, Druyan discussed 4970 Druyan and the asteroid named after her late husband, saying that 4970 Druyan is in a "wedding ring orbit" around the Sun with 2709 Sagan. Druyan was presented with a plaque on Sagan's sixtieth birthday, which is inscribed: "Asteroid 2709 Sagan in eternal companion orbit with asteroid 4970 Druyan, symbolic of their love and admiration for each other."

In 2000, Druyan, together with Steve Soter, co-wrote Passport to the Universe, the inaugural planetarium show for the Rose Center for Earth and Space at the American Natural History Museum's Hayden Planetarium. The attraction is narrated by Tom Hanks. Druyan and Soter also co-wrote The Search for Life: Are We Alone, narrated by Harrison Ford, which also debuted at the Hayden's Rose Center.

In 2000, Druyan co-founded Cosmos Studios, Inc, with Joseph Firmage. As CEO of Cosmos Studios, Druyan produces science-based entertainment for all media. In addition to Cosmos: A SpaceTime Odyssey, Cosmos Studios has produced Cosmic Africa, Lost Dinosaurs of Egypt, and the Emmy-nominated documentary Cosmic Journey: The Voyager Interstellar Mission and Message. In 2009, she distributed a series of podcasts called At Home in the Cosmos with Annie Druyan, in which she described her works, the life of her husband, Carl Sagan, and their marriage.

Druyan served as program director of the first solar-sail deep-space mission, Cosmos 1, launched on a Russian ICBM in 2005.

In November 2006, Druyan was a speaker at "Beyond Belief: Science, Religion, Reason and Survival".

In January 2007, she was a juror at the 2007 Sundance Film Festival, responsible for selecting the winner of the Alfred P. Sloan Prize for films about science and technology.

In November 2007, Druyan was awarded the title of "Humanist Laureate" by the International Academy of Humanism.

In 2011, it was announced that Druyan would executive produce, co-write, and be one of the episodic directors for a sequel to Cosmos: A Personal Voyage, to be called Cosmos: A Spacetime Odyssey, which began airing in March 2014. Episodes premiered on Fox and also aired on National Geographic Channel on the following night. At the time of its release, Fox gave the series the largest global rollout of a television series ever, debuting it in 180 countries. The premiere episode was shown across nine of Fox's cable properties in addition to the broadcast network in a "roadblock" style premiere. The series went on to become the most-watched series ever for National Geographic Channel International, with at least some part of the 13-episode series watched by 135 million people, including 45 million in the U.S.

In October 2019, the Center for Inquiry West opened the Carl Sagan and Ann Druyan Theater in Los Angeles.

In February 2020, Druyan published Cosmos: Possible Worlds, a companion volume to the television series of the same name, which premiered in March 2020.

In March 2020, a third season of Cosmos, named Cosmos: Possible Worlds, for which Druyan was executive producer, writer, and director, premiered on National Geographic. Druyan also said: "I very much have season four in mind, and I know what it’s going to be. And I even know some of the stories that I want to tell in it."

In 2020, Sagan and Druyan's daughter Sasha Sagan released a book For Small Creatures Such As We: Rituals for Finding Meaning in our Unlikely World, which discusses life with her parents and her father's death when she was fourteen years old.