In 1980, Eldritch and Gary Marx formed the Sisters of Mercy. On the first single, "Damage Done/Watch/Home of the Hit-men", Eldritch played the drums, a task he was later relieved of by a series of drum machines referred to as Doktor Avalanche, allowing him instead to focus on his vocal performance. Over the years, nine members have left the group, several of them citing conflicts with the frontman as a reason for their departure. These former members include Patricia Morrison, who claimed she had been paid an average of £300 per month; and Wayne Hussey, with whom Eldritch had a personal feud which contributed to heavy criticism of both by the popular music press during the 1980s. Hussey formed a breakaway band called The Mission as a result of this conflict.
Though Andrew Eldritch has been called the "Godfather of Goth", for inspiring and defining the gothic scene musically and aesthetically, the Sisters of Mercy, despite being formed in 1980, were originally not very popular in the early-1980s post-punk subgenre of bands and music fans which the British press had labelled Goth. The Sisters of Mercy were, however, accused by the press of plagiarising Joy Division, who were marketed by their management as "gothic" in the late 1970s.