Shortly after the war, General Charles de Gaulle appointed Malraux as his Minister for Information (1945–1946). Soon after, he completed his first book on art, The Psychology of Art, published in three volumes (1947–1949). The work was subsequently revised and republished in one volume as The Voices of Silence (Les Voix du Silence), the first part of which has been published separately as The Museum without Walls. Other important works on the theory of art were to follow. These included the three-volume Metamorphosis of the Gods and Precarious Man and Literature, the latter published posthumously in 1977. In 1948, Malraux married a second time, to Marie-Madeleine Lioux, a concert pianist and the widow of his half-brother, Roland Malraux. They separated in 1966. Subsequently, Malraux lived with Louise de Vilmorin in the Vilmorin family château at Verrières-le-Buisson, Essonne, a suburb southwest of Paris. Vilmorin was best known as a writer of delicate but mordant tales, often set in aristocratic or artistic milieu. Her most famous novel was Madame de..., published in 1951, which was adapted into the celebrated film The Earrings of Madame de… (1953), directed by Max Ophüls and starring Charles Boyer, Danielle Darrieux and Vittorio de Sica. Vilmorin's other works included Juliette, La lettre dans un taxi, Les belles amours, Saintes-Unefois, and Intimités. Her letters to Jean Cocteau were published after the death of both correspondents. After Louise's death, Malraux spent his final years with her relative, Sophie de Vilmorin.
During this post-war period, Malraux published a series of semi-autobiographical works, the first entitled Antimémoires (1967). A later volume in the series, Lazarus, is a reflection on death occasioned by his experiences during a serious illness. La Tête d'obsidienne (1974) (translated as Picasso's Mask) concerns Picasso, and visual art more generally. In his last book, published posthumously in 1977, L'Homme précaire et la littérature, Malraux propounded the theory that there was a bibliothèque imaginaire where writers created works that influenced subsequent writers much as painters learned their craft by studying the old masters; once they have understood the work of the old masters, writers would sally forth with the knowledge gained to create new works that added to the growing and never-ending bibliothèque imaginaire. An elitist who appreciated what he saw as the high culture of all the nations of the world, Malraux was especially interested in art history and archaeology, and saw his duty as a writer to share what he knew with ordinary people. An aesthete, Malraux believed that art was spiritually enriching and necessary for humanity.