Kirchner worked as a teacher and social worker, holding a PhD in social work. From 1975 to 1983 she served as a sub-secretary of social action in her native Santa Cruz Province. From 1987 to 1990 she was a minister in the municipality of Río Gallegos, leading on public health, education, culture, social action, recreation and sport. For a few months in 1990, and again between 1991 and 1995 she served as provincial minister for social affairs, under her brother who had been elected governor of Santa Cruz.